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Revolutionizing the future of neurodegenerative disease treatment by unlocking the potential of plant-based protein folding and degradation mechanisms, offering pioneering therapies for rare and untreatable age-related protein aggregation disorders like Huntington’s disease

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Explanatory Video: Project Overview


https://www.youtube.com/watch?v=MDr0_VwgrWQ

Plantman's Mission


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Our mission at Plantman is to revolutionize the treatment of Huntington's disease, a devastating hereditary condition characterized by involuntary movements, cognitive decline, and ultimately, premature death. Currently, there is no cure for this debilitating disease.

Drawing inspiration from the remarkable resilience of plants against harmful protein aggregates, we have identified a groundbreaking plant protein with the potential to suppress the toxic proteins associated with Huntington's disease.

Our primary objective is to engineer SPP, a plant-derived protein, to specifically target and break down the harmful protein aggregates in patients. This innovative therapeutic approach holds the promise of potentially curing Huntington's disease for the first time, offering hope to patients and families affected by this condition.

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Pitch Video: BioRiver Boost 2023 Runner-Up


https://youtu.be/OlZeSIPc0Ws

Nature Aging Publication


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In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation

Featured on Nature Aging Cover